Low geriatric nutritional risk index predicts poor prognosis in patients with cirrhosis: a retrospective study

Aim Malnutrition, which increases the risk of liver disease-related events and mortality, is a serious complication in cirrhosis. This study aimed to investigate whether geriatric nutritional index (GNRI) could predict long-term prognosis patients with Methods We retrospectively evaluated 266 cirrhosis classified them into two groups based on baseline GNRI scores: (≤98, n = 104) no-risk (>98, 162). The cumulative survival rates were compared between compensated decompensated cirrhosis, respectively. Cox proportional hazards regression analysis was used identify significant independent factors associated mortality. Results median observation period 54.9 (33.6–61.7) months 65 (24.4%) deaths occurred during follow-up period. scores significantly inversely correlated Child-Pugh score ( r −0.579), model for end-stage disease −0.286), Mac-2 binding protein glycosylation isomer −0.494). Multivariate identified low as factor mortality [overall cohort: hazard ratio (HR), 0.926; p < 0.001; cirrhosis: HR, 0.947; 0.003; 0.923; 0.001]. group demonstrated lower than overall cohort, 0.001, <0.001, 0.013, respectively). Conclusion Low poor both Therefore, simple useful tool predicting modifying status